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Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

AIM: To examine the activation of the Nalp3 inflammasome and its downstream targets following lipopolysaccharide (LPS)-induced stimulation in the liver. METHODS: Six-to-eight-week-old C57BL/6 chow fed mice were injected intraperitoneally with 0.5 μg/g bodyweight LPS and sacrificed 2, 4, 6, 18 or 24...

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Autors principals: Ganz, Michal, Csak, Timea, Nath, Bharath, Szabo, Gyongyi
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229625/
https://ncbi.nlm.nih.gov/pubmed/22147977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i43.4772
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