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Concentration Dependent Ion Selectivity in VDAC: A Molecular Dynamics Simulation Study

The voltage-dependent anion channel (VDAC) forms the major pore in the outer mitochondrial membrane. Its high conducting open state features a moderate anion selectivity. There is some evidence indicating that the electrophysiological properties of VDAC vary with the salt concentration. Using a theo...

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Autors principals: Krammer, Eva-Maria, Homblé, Fabrice, Prévost, Martine
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229507/
https://ncbi.nlm.nih.gov/pubmed/22164223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027994
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