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Aberrant Hedgehog Ligands Induce Progressive Pancreatic Fibrosis by Paracrine Activation of Myofibroblasts and Ductular Cells in Transgenic Zebrafish

Hedgehog (Hh) signaling is frequently up-regulated in fibrogenic pancreatic diseases including chronic pancreatitis and pancreatic cancer. Although recent series suggest exclusive paracrine activation of stromal cells by Hh ligands from epithelial components, debates still exist on how Hh signaling...

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Bibliografski detalji
Glavni autori: Jung, In Hye, Jung, Dawoon E., Park, Young Nyun, Song, Si Young, Park, Seung Woo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229500/
https://ncbi.nlm.nih.gov/pubmed/22164219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027941
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