Mice Null for Calsequestrin 1 Exhibit Deficits in Functional Performance and Sarcoplasmic Reticulum Calcium Handling

In skeletal muscle, the release of calcium (Ca(2+)) by ryanodine sensitive sarcoplasmic reticulum (SR) Ca(2+) release channels (i.e., ryanodine receptors; RyR1s) is the primary determinant of contractile filament activation. Much attention has been focused on calsequestrin (CASQ1) and its role in SR...

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Bibliografiska uppgifter
Huvudupphovsmän: Olojo, Rotimi O., Ziman, Andrew P., Hernández-Ochoa, Erick O., Allen, Paul D., Schneider, Martin F., Ward, Christopher W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229475/
https://ncbi.nlm.nih.gov/pubmed/22164205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027036
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