Nicotinamide Inhibits Alkylating Agent-Induced Apoptotic Neurodegeneration in the Developing Rat Brain

BACKGROUND: Exposure to the chemotherapeutic alkylating agent thiotepa during brain development leads to neurological complications arising from neurodegeneration and irreversible damage to the developing central nerve system (CNS). Administration of single dose of thiotepa in 7-d postnatal (P7) rat...

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Autors principals: Ullah, Najeeb, Lee, Hae Young, Naseer, Muhammad Imran, Ullah, Ikram, Suh, Joo Won, Kim, Myeong Ok
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229474/
https://ncbi.nlm.nih.gov/pubmed/22164206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027093
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