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Structural insights into the recognition mechanism between an antitumor galectin AAL and the Thomsen-Friedenreich antigen

Thomsen-Friedenreich (TF) antigen, which plays an important role in the regulation of cancer cell proliferation, occurs in ∼90% of all human cancers and precancerous conditions. Although TF antigen has been known for almost 80 yr as a pancarcinoma antigen, the recognition mechanism between TF antige...

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Bibliografiske detaljer
Main Authors: Feng, Lei, Sun, Hui, Zhang, Ying, Li, De-Feng, Wang, Da-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229422/
https://ncbi.nlm.nih.gov/pubmed/20530247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-159111
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