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Ozonolysis of the double bond of the unsaturated uronate residue in low-molecular-weight heparin and K5 heparosan

Ozone is known to add across and cleave carbon–carbon double bonds. Ozonolysis is widely used for the preparation of pharmaceuticals, for bleaching substances and for killing microorganisms in air and water sources. Some polysaccharides and oligosaccharides, such as those prepared using chemical or...

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Bibliographic Details
Main Authors: Masuko, Sayaka, Higashi, Kyohei, Wang, Zhenyu, Bhaskar, Ujjwal, Hickey, Anne Marie, Zhang, Fuming, Toida, Toshihiko, Dordick, Jonathan, Linhardt, Robert J.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229283/
https://ncbi.nlm.nih.gov/pubmed/21742314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2011.06.004
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