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Anti-Tumor Activity of Peptide Amphiphile Nanofiber-Encapsulated Camptothecin

Self-assembling peptide amphiphile (PA) nanofibers were used to encapsulate camptothecin (CPT), a naturally occurring hydrophobic chemotherapy agent, using a solvent evaporation technique. Encapsulation by PA nanofibers was found to improve the aqueous solubility of the CPT molecule by more than 50-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Soukasene, Stephen, Toft, Daniel J., Moyer, Tyson J., Lu, Hsuming, Lee, Hyung-Kun, Standley, Stephany M., Cryns, Vincent L., Stupp, Samuel I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229267/
https://ncbi.nlm.nih.gov/pubmed/22044255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn203343z
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