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Self-assembled peptide nanostructures targeting death receptor 5 and encapsulating paclitaxel as a multifunctional cancer therapy

The development of tumor-targeted nanoscale carriers for the delivery of cancer therapeutics offers the ability to increase efficacy while limiting off-target toxicity. In this work we focused on targeting death receptor 5 (DR5), which is highly expressed by cancer cells, and upon binding, triggers...

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Detalhes bibliográficos
Publicado no:ACS Biomater Sci Eng
Main Authors: Moyer, Tyson J., Chen, Feng, Toft, Daniel J., Ruff, Yves, Cryns, Vincent L., Stupp, Samuel I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725269/
https://ncbi.nlm.nih.gov/pubmed/33304996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.9b01259
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