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Stimulation of aortic smooth muscle cell mitogenesis by serotonin.

Bovine aortic smooth muscle cells in vitro responded to 1 nM to 10 microM serotonin with increased incorporation of [3H]thymidine into DNA. The mitogenic effect of serotonin was half-maximal at 80 nM and maximal above 1 microM. At a concentration of 1 microM, serotonin stimulated smooth muscle cell...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nemecek, G M, Coughlin, S R, Handley, D A, Moskowitz, M A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322926/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.674
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