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Purification and assay of a 145-kDa protein (STOP145) with microtubule-stabilizing and motility behavior.

The capacity of microtubules to disassemble in vitro is profoundly affected by a protein factor designated STOP (stable tubule only polypeptide). Here we report the isolation of STOP protein and confirm that its activity is, as predicted, highly substoichiometric to the tubulin in microtubules. The...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Margolis, R L, Rauch, C T, Job, D
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322919/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456161/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.639
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