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Total synthesis of a gene for bovine rhodopsin.

To carry out systematic structure-function studies of bovine rhodopsin by specific amino acid replacements, we have accomplished the total synthesis of its gene, which is 1057 base pairs long. The synthetic gene contains 28 unique restriction sites that are on the average 60 base pairs apart. Replac...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Ferretti, L, Karnik, S S, Khorana, H G, Nassal, M, Oprian, D D
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1986
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.599
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