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Total synthesis of a gene for bovine rhodopsin.

To carry out systematic structure-function studies of bovine rhodopsin by specific amino acid replacements, we have accomplished the total synthesis of its gene, which is 1057 base pairs long. The synthetic gene contains 28 unique restriction sites that are on the average 60 base pairs apart. Replac...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Ferretti, L, Karnik, S S, Khorana, H G, Nassal, M, Oprian, D D
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3456156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.3.599
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