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Small Molecule Anti-Angiogenic Probes of the Ubiquitin Proteasome Pathway: Potential Application to Choroidal Neovascularization

PURPOSE: To characterize the angiogenic and inflammatory responses of human choroidal endothelial cells (HCECs) to stimulators and inhibitors of the ubiquitin proteasome pathway (UPP). METHODS: The regulation of the UPP by the inhibitor withaferin A and its congener, withanolide D, two natural produ...

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Bibliografiske detaljer
Main Authors: Bargagna-Mohan, Paola, Ravindranath, Padma Priya, Mohan, Royce
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229038/
https://ncbi.nlm.nih.gov/pubmed/16936134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-1452
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