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Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice

Mycobacterium tuberculosis genome contains four related sets of an operon called mce (mce1-4). The disruption of one of these operons, mce1, causes M. tuberculosis to become hypervirulent, whereas the mce3 and mce4 operon mutants are attenuated in mice. This study examined the phenotype of the mce2...

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Bibliografiske detaljer
Main Authors: Marjanovic, Olivera, Miyata, Toshiko, Goodridge, Amador, Kendall, Lon V., Riley, Lee W.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228843/
https://ncbi.nlm.nih.gov/pubmed/19963438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2009.10.004
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