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Comparative metabolic profiling of mce1 operon mutant vs wild-type Mycobacterium tuberculosis strains

Mycobacterium tuberculosis disrupted in a 13-gene operon (mce1) accumulates free mycolic acids (FM) in its cell wall and causes accelerated death in mice. Here, to more comprehensively analyze differences in their cell wall lipid composition, we used an untargeted metabolomics approach to compare th...

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Publicat a:Pathog Dis
Autors principals: Queiroz, Adriano, Medina-Cleghorn, Daniel, Marjanovic, Olivera, Nomura, Daniel K., Riley, Lee W.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626588/
https://ncbi.nlm.nih.gov/pubmed/26319139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv066
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