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Comparative metabolic profiling of mce1 operon mutant vs wild-type Mycobacterium tuberculosis strains

Mycobacterium tuberculosis disrupted in a 13-gene operon (mce1) accumulates free mycolic acids (FM) in its cell wall and causes accelerated death in mice. Here, to more comprehensively analyze differences in their cell wall lipid composition, we used an untargeted metabolomics approach to compare th...

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Detalhes bibliográficos
Publicado no:Pathog Dis
Main Authors: Queiroz, Adriano, Medina-Cleghorn, Daniel, Marjanovic, Olivera, Nomura, Daniel K., Riley, Lee W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626588/
https://ncbi.nlm.nih.gov/pubmed/26319139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv066
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