Direct Sensing of Endothelial Oxidants by Vascular Endothelial Growth Factor Receptor-2 and c-Src

BACKGROUND: ADPH oxidase-derived reactive oxygen species (ROS) play important roles in redox homeostasis and signal transduction in endothelial cells (ECs). We previously demonstrated that c-Src plays a key role in VEGF-induced, ROS-dependent selective activation of PI3K-Akt but not PLCγ-1-ERK1/2 si...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Monica, Choy, Wing C., Abid, Md. Ruhul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228784/
https://ncbi.nlm.nih.gov/pubmed/22145046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028454
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