Vascular Endothelial Growth Factor Receptor-1 Modulates Vascular Endothelial Growth Factor-Mediated Angiogenesis via Nitric Oxide

The known responses of vascular endothelial growth factor (VEGF) are mediated through VEGF receptor-2 (VEGFR-2/KDR) in endothelial cells. However, it is unknown whether VEGFR-1 (Flt-1) is an inert decoy or a signaling receptor for VEGF during physiological or pathological angiogenesis. Here we repor...

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Main Authors: Bussolati, Benedetta, Dunk, Caroline, Grohman, Malcolm, Kontos, Christopher D., Mason, Justin, Ahmed, Asif
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2001
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850457/
https://ncbi.nlm.nih.gov/pubmed/11549592
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