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Down-Regulation of DNA Mismatch Repair Enhances Initiation and Growth of Neuroblastoma and Brain Tumour Multicellular Spheroids

Multicellular tumour spheroid (MCTS) cultures are excellent model systems for simulating the development and microenvironmental conditions of in vivo tumour growth. Many documented cell lines can generate differentiated MCTS when cultured in suspension or in a non-adhesive environment. While physiol...

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Sonraí Bibleagrafaíochta
Main Authors: Collins, Samuel L., Hervé, Rodolphe, Keevil, C. W., Blaydes, Jeremy P., Webb, Jeremy S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228745/
https://ncbi.nlm.nih.gov/pubmed/22145025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028123
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