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Down-Regulation of DNA Mismatch Repair Enhances Initiation and Growth of Neuroblastoma and Brain Tumour Multicellular Spheroids

Multicellular tumour spheroid (MCTS) cultures are excellent model systems for simulating the development and microenvironmental conditions of in vivo tumour growth. Many documented cell lines can generate differentiated MCTS when cultured in suspension or in a non-adhesive environment. While physiol...

詳細記述

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書誌詳細
主要な著者: Collins, Samuel L., Hervé, Rodolphe, Keevil, C. W., Blaydes, Jeremy P., Webb, Jeremy S.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228745/
https://ncbi.nlm.nih.gov/pubmed/22145025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028123
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