Down-Regulation of DNA Mismatch Repair Enhances Initiation and Growth of Neuroblastoma and Brain Tumour Multicellular Spheroids

Multicellular tumour spheroid (MCTS) cultures are excellent model systems for simulating the development and microenvironmental conditions of in vivo tumour growth. Many documented cell lines can generate differentiated MCTS when cultured in suspension or in a non-adhesive environment. While physiol...

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Main Authors: Collins, Samuel L., Hervé, Rodolphe, Keevil, C. W., Blaydes, Jeremy P., Webb, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228745/
https://ncbi.nlm.nih.gov/pubmed/22145025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028123
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