Protection against Fas-induced fulminant hepatic failure in liver specific integrin linked kinase knockout mice

BACKGROUND: Programmed cell death or apoptosis is an essential process for tissue homeostasis. Hepatocyte apoptosis is a common mechanism to many forms of liver disease. This study was undertaken to test the role of ILK in hepatocyte survival and response to injury using a Jo-2-induced apoptosis mod...

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Bibliographic Details
Main Authors: Donthamsetty, Shashikiran, Mars, Wendy M, Orr, Anne, Wu, Chuanyue, Michalopoulos, George K
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228663/
https://ncbi.nlm.nih.gov/pubmed/22104495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-10-11
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