Integrin-linked kinase is involved in matrix-induced hepatocyte differentiation

Hepatocytes have restricted proliferative capacity in culture and when cultured without matrix, lose the hepatocyte-specific gene expression and characteristic cellular micro-architecture. Overlay of matrix-preparations on de-differentiated hepatocytes restores differentiation. Integrin-linked kinas...

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Hlavní autoři: Gkretsi, Vasiliki, Bowen, William C., Yang, Yu, Wu, Chuanyue, Michalopoulos, George K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769419/
https://ncbi.nlm.nih.gov/pubmed/17194454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.12.091
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