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Insulin-Like Growth Factor I–Mediated Skeletal Muscle Hypertrophy Is Characterized by Increased mTOR-p70S6K Signaling without Increased Akt Phosphorylation
BACKGROUND: Insulin-like growth factor I (IGF-I) is an anabolic hormone that is known to induce skeletal muscle hypertrophy. However, the signaling pathways mediating IGF-I's hypertrophic effect in vivo are unknown. METHOD: The phosphorylation of 46 proteins was investigated by Kinetworks prote...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228637/ https://ncbi.nlm.nih.gov/pubmed/15921033 |
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