Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells

Despite several side effects, glucocorticoids (GCs) have been widely used for 60 y to treat rheumatoid arthritis on the basis of their antiinflammatory effects. However, the cells targeted by GCs and the transcriptional mechanisms underlying their actions through the glucocorticoid receptor (GR) in...

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Bibliographische Detailangaben
Hauptverfasser: Baschant, Ulrike, Frappart, Lucien, Rauchhaus, Una, Bruns, Lisa, Reichardt, Holger M., Kamradt, Thomas, Bräuer, Rolf, Tuckermann, Jan P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228447/
https://ncbi.nlm.nih.gov/pubmed/22084093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105857108
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