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Purification of a terminal uridylyltransferase that acts as host factor in the in vitro poliovirus replicase reaction.

Poliovirus RNA polymerase requires a host factor to initiate RNA synthesis in vitro. The host factor was previously purified to near homogeneity from HeLa cells but was not assigned an enzymatic activity. This report describes the purification of a terminal uridylyltransferase that can act as host f...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Andrews, N C, Baltimore, D
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2417240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.221
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