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Antibody to a host protein prevents initiation by the poliovirus replicase.

In vitro transcription of poliovirus RNA was catalyzed by the combination of a virus-coded polymerase and a host cell protein (host factor). Antibody to host factor inhibited template-dependent synthesis of complementary RNA where presumably RNA chain initiation occurred. On the contrary, elongation...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Dasgupta, A, Hollingshead, P, Baltimore, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6284991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.42.3.1114-1117.1982
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