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Antibody to a host protein prevents initiation by the poliovirus replicase.

In vitro transcription of poliovirus RNA was catalyzed by the combination of a virus-coded polymerase and a host cell protein (host factor). Antibody to host factor inhibited template-dependent synthesis of complementary RNA where presumably RNA chain initiation occurred. On the contrary, elongation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dasgupta, A, Hollingshead, P, Baltimore, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC256952/
https://ncbi.nlm.nih.gov/pubmed/6284991
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