Antibody to a host protein prevents initiation by the poliovirus replicase.
In vitro transcription of poliovirus RNA was catalyzed by the combination of a virus-coded polymerase and a host cell protein (host factor). Antibody to host factor inhibited template-dependent synthesis of complementary RNA where presumably RNA chain initiation occurred. On the contrary, elongation...
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| Pubblicato in: | J Virol |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1982
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6284991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.42.3.1114-1117.1982 |
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