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Optimizing Chemotherapy Dose and Schedule by Norton-Simon Mathematical Modeling
BACKGROUND: To hasten and improve anticancer drug development, we created a novel approach to generating and analyzing preclinical dose-scheduling data so as to optimize benefit-to-toxicity ratios. METHODS: We applied mathematical methods based upon Norton-Simon growth kinetic modeling to tumor-volu...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228251/ https://ncbi.nlm.nih.gov/pubmed/20519801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/BD-2009-0290 |
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