Phencyclidine in low doses selectively blocks a presynaptic voltage-regulated potassium channel in rat brain.
Phencylidine (PCP) is a major drug of abuse in the United States. It produces a toxic confusional psychosis in man. We show here that nanomolar to micromolar concentrations of PCP and behaviorally active congeners selectively block voltage-regulated noninactivating (or very slowly inactivating) pres...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1986
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2417237/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.1.189 |
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