Clinical Relevance of the Dose of Cytarabine in the Upfront Treatment of Primary CNS Lymphomas with Methotrexate-Cytarabine Combination

BACKGROUND. The combination of high doses of methotrexate (MTX) and cytarabine (araC) is the standard chemotherapy for patients with primary CNS lymphoma (PCNSL). The addition of an alkylating agent could improve MTX-araC efficacy because it is active against quiescent G0 cells and increases antimet...

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Bibliografische gegevens
Hoofdauteurs: Ferreri, Andrés J. M., Licata, Giada, Foppoli, Marco, Corazzelli, Gaetano, Zucca, Emanuele, Stelitano, Caterina, Zaja, Francesco, Fava, Sergio, Paolini, Rossella, Franzin, Alberto, Politi, Letterio S., Ponzoni, Maurilio, Reni, Michele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AlphaMed Press 2011
Onderwerpen:
Lymphoma
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228098/
https://ncbi.nlm.nih.gov/pubmed/21346023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0361
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