Clinical Relevance of the Dose of Cytarabine in the Upfront Treatment of Primary CNS Lymphomas with Methotrexate-Cytarabine Combination

BACKGROUND. The combination of high doses of methotrexate (MTX) and cytarabine (araC) is the standard chemotherapy for patients with primary CNS lymphoma (PCNSL). The addition of an alkylating agent could improve MTX-araC efficacy because it is active against quiescent G0 cells and increases antimet...

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Autors principals: Ferreri, Andrés J. M., Licata, Giada, Foppoli, Marco, Corazzelli, Gaetano, Zucca, Emanuele, Stelitano, Caterina, Zaja, Francesco, Fava, Sergio, Paolini, Rossella, Franzin, Alberto, Politi, Letterio S., Ponzoni, Maurilio, Reni, Michele
Format: Artigo
Idioma:Inglês
Publicat: AlphaMed Press 2011
Matèries:
Lymphoma
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228098/
https://ncbi.nlm.nih.gov/pubmed/21346023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0361
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