The Role of HER-3 Expression in the Prediction of Clinical Outcome for Advanced Colorectal Cancer Patients Receiving Irinotecan and Cetuximab

Preclinical data suggested that, in the presence of human epidermal growth factor receptor (HER)-3–altered activation, colorectal cancer cells may escape anti–epidermal growth factor receptor (EGFR)-mediated cell death. HER-3 overexpression may then represent a key factor for resistance to anti-EGFR...

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Detalhes bibliográficos
Main Authors: Scartozzi, Mario, Mandolesi, Alessandra, Giampieri, Riccardo, Bittoni, Alessandro, Pierantoni, Chiara, Zaniboni, Alberto, Galizia, Eva, Giustini, Lucio, Silva, Rosa Rita, Bisonni, Renato, Berardi, Rossana, Biscotti, Tommasina, Biagetti, Simona, Bearzi, Italo, Cascinu, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2011
Assuntos:
Gastrointestinal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228051/
https://ncbi.nlm.nih.gov/pubmed/21212430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0119
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