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Anti-Vascular Endothelial Growth Factor Therapies and Cardiovascular Toxicity: What Are the Important Clinical Markers to Target?

BACKGROUND. Therapies targeting vascular endothelial growth factor (VEGF) are associated with hypertension, cardiotoxicity, and thromboembolic events. METHODS. All prospective phase I–III clinical trials published up to December 2008 of approved anti-VEGF therapies (bevacizumab, sunitinib, sorafenib...

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Autors principals: Vaklavas, Christos, Lenihan, Daniel, Kurzrock, Razelle, Tsimberidou, Apostolia Maria
Format: Artigo
Idioma:Inglês
Publicat: AlphaMed Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227935/
https://ncbi.nlm.nih.gov/pubmed/20139170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2009-0252
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