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Anti-Vascular Endothelial Growth Factor Therapies and Cardiovascular Toxicity: What Are the Important Clinical Markers to Target?

BACKGROUND. Therapies targeting vascular endothelial growth factor (VEGF) are associated with hypertension, cardiotoxicity, and thromboembolic events. METHODS. All prospective phase I–III clinical trials published up to December 2008 of approved anti-VEGF therapies (bevacizumab, sunitinib, sorafenib...

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Detalhes bibliográficos
Main Authors: Vaklavas, Christos, Lenihan, Daniel, Kurzrock, Razelle, Tsimberidou, Apostolia Maria
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227935/
https://ncbi.nlm.nih.gov/pubmed/20139170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2009-0252
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