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Hemoglobin Long Island is caused by a single mutation (adenine to cytosine) resulting in a failure to cleave amino-terminal methionine.

Hemoglobin Long Island has two separate amino acid abnormalities of beta-globin structure: an extension of the NH2 terminus by a methionine residue and a histidine-to-proline substitution at the normal second position. The NH2-terminal methionine residue, the translation product of an AUG initiation...

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Bibliografische gegevens
Hoofdauteurs: Prchal, J T, Cashman, D P, Kan, Y W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC322783/
https://ncbi.nlm.nih.gov/pubmed/3455755
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