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Specific knockdown of the D2 Long dopamine receptor variant

Dopamine signaling in the nucleus accumbens is critical in mediating the effects of cocaine. There are two splice variants of dopamine D2 receptors, D2L and D2S, which are believed to have different functional roles. Here we show that knocking down D2L selectively using viral mediated shRNA led to a...

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Detalhes bibliográficos
Main Authors: Naughton, Bart J., Thirtamara-Rajamani, Keerthi, Wang, Chuansong, During, Matthew J, Gu, Howard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227782/
https://ncbi.nlm.nih.gov/pubmed/22082989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e32834d2216
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