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Non-visual arrestins function as simple scaffolds assembling the MKK4–JNK3a2 signaling complex

Arrestins are a small family of proteins with four mammalian members that play key roles in the regulation of multiple GPCR-dependent and -independent signaling pathways. Although arrestins were reported to serve as scaffolds for MAP kinase cascades, promoting the activation of JNK3, ERK1/2, and p38...

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Autors principals: Zhan, Xuanzhi, Kaoud, Tamer S., Dalby, Kevin N., Gurevich, Vsevolod V.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227541/
https://ncbi.nlm.nih.gov/pubmed/22047447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201506g
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