Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion (I/R) model

OBJECTIVE: ABCC6 genetic deficiency underlies Pseudoxanthoma elasticum (PXE) in humans, characterized by ectopic calcification, and early cardiac disease. The spectrum of PXE has been noted in Abcc6 deficient mice, including dystrophic cardiac calcification. We tested the role of Abcc6 in response t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mungrue, Imran N., Zhao, Peng, Yao, Yucheng, Meng, Haijin, Rau, Christoph, Havel, Jocelyn V., Gorgels, Theo G.M.F., Bergen, Arthur A.B., MacLellan, W. Robb, Drake, Thomas A, Boström, Kristina I., Lusis, Aldons J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227394/
https://ncbi.nlm.nih.gov/pubmed/21979437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.237420
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