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Diminished synthesis of an alpha chain mutant, hemoglobin I (α(16 lys → glu))

In patients heterozygous for abnormal hemoglobins there is usually less than 50% of the mutant hemoglobin present in peripheral blood. The synthetic rates of α-chain mutants compared to α(A) have not been reported to date. In this study the production of α(A)- and α(I)-chains has been measured in pe...

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Autori principali: Esan, G. J. Folayan, Morgan, F. J., O'Donnell, J. V., Ford, S., Bank, A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1970
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC322722/
https://ncbi.nlm.nih.gov/pubmed/5480848
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