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Urokinase Receptor and Fibronectin Regulate the ERK(MAPK) to p38(MAPK) Activity Ratios That Determine Carcinoma Cell Proliferation or Dormancy In Vivo

We discovered that a shift between the state of tumorigenicity and dormancy in human carcinoma (HEp3) is attained through regulation of the balance between two classical mitogen-activated protein kinase (MAPK)-signaling pathways, the mitogenic extracellular regulated kinase (ERK) and the apoptotic/g...

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Detalles Bibliográficos
Main Authors: Aguirre-Ghiso, Julio A., Liu, David, Mignatti, Andrea, Kovalski, Katherine, Ossowski, Liliana
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC32272/
https://ncbi.nlm.nih.gov/pubmed/11294892
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