Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

Using an integrative genomics approach called Amplification Breakpoint Ranking and Assembly (ABRA) analysis, we nominated KRAS as a gene fusion with the ubiquitin-conjugating enzyme UBE2L3 in the DU145 cell line, originally derived from prostate cancer metastasis to the brain. Interestingly, analysi...

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Main Authors: Wang, Xiao-Song, Shankar, Sunita, Dhanasekaran, Saravana M., Ateeq, Bushra, Sasaki, Atsuo T., Jing, Xiaojun, Robinson, Daniel, Cao, Qi, Prensner, John R., Yocum, Anastasia K., Wang, Rui, Fries, Daniel F., Han, Bo, Asangani, Irfan A., Cao, Xuhong, Li, Yong, Omenn, Gilbert S., Pflueger, Dorothee, Gopalan, Anuradha, Reuter, Victor E., Kahoud, Emily Rose, Cantley, Lewis C., Rubin, Mark A., Palanisamy, Nallasivam, Varambally, Sooryanarayana, Chinnaiyan, Arul M.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227139/
https://ncbi.nlm.nih.gov/pubmed/22140652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8274.CD-10-0022
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