Cargando...

Delineation of key regulatory elements identifies points of vulnerability in the mitogen-activated signaling network

Drug development efforts against cancer are often hampered by the complex properties of signaling networks. Here we combined the results of an RNAi screen targeting the cellular signaling machinery, with graph theoretical analysis to extract the core modules that process both mitogenic and oncogenic...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jailkhani, Noor, Ravichandran, Srikanth, Hegde, Shubhada R., Siddiqui, Zaved, Mande, Shekhar C., Rao, Kanury V.S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227097/
https://ncbi.nlm.nih.gov/pubmed/21865350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.116145.110
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!