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Some natural flavonoids are competitive inhibitors of Caspase-1, −3 and −7 despite their cellular toxicity

A common feature of both apoptosis and inflammation is the activation of caspases. Caspases are aspartate-directed cysteine proteases that have numerous cellular targets. It has been discovered that several flavonoids are inhibitors of caspases. Flavonoids are members of a family of polyphenolic com...

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Detalhes bibliográficos
Main Authors: White, J. Brandon, Beckford, Jeremy, Yadegarynia, Sina, Ngo, Nhi, Lialiutska, Tetiana, d’Alarcao, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226999/
https://ncbi.nlm.nih.gov/pubmed/22140296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.foodchem.2011.10.026
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