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Some natural flavonoids are competitive inhibitors of Caspase-1, −3 and −7 despite their cellular toxicity
A common feature of both apoptosis and inflammation is the activation of caspases. Caspases are aspartate-directed cysteine proteases that have numerous cellular targets. It has been discovered that several flavonoids are inhibitors of caspases. Flavonoids are members of a family of polyphenolic com...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226999/ https://ncbi.nlm.nih.gov/pubmed/22140296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.foodchem.2011.10.026 |
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