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Sterols for Oxygen: A Metabolic Burden for Microbial SREBP
In this issue of Molecular Cell, Lee et al. (2011) report a novel mechanism for oxygen-sensing in S. pombe, whereby the 2-OG-Fe(II) dioxygenase Ofd protein regulates both the DNA binding activity and the degradation of the hypoxia regulated transcription factor, Sre1p.
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226767/ https://ncbi.nlm.nih.gov/pubmed/22017866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.10.004 |
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