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MicroRNA-16 and MicroRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting VEGFR2 and FGFR1

OBJECTIVE: microRNAs play key roles in modulating a variety of cellular processes by post-transcriptional regulation of their target genes. VEGF, VEGFR-2 and FGFR-1 were identified by bioinformatic approaches and subsequently validated as targets of miR-16 and miR-424 in endothelial cells (ECs). RES...

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書誌詳細
主要な著者: Chamorro-Jorganes, Aránzazu, Araldi, Elisa, Penalva, Luiz O. F., Sandhu, Devraj, Fernández-Hernando, Carlos, Suárez, Yajaira
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226744/
https://ncbi.nlm.nih.gov/pubmed/21885851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.236521
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