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MicroRNA-16 and MicroRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting VEGFR2 and FGFR1
OBJECTIVE: microRNAs play key roles in modulating a variety of cellular processes by post-transcriptional regulation of their target genes. VEGF, VEGFR-2 and FGFR-1 were identified by bioinformatic approaches and subsequently validated as targets of miR-16 and miR-424 in endothelial cells (ECs). RES...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226744/ https://ncbi.nlm.nih.gov/pubmed/21885851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.236521 |
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