Effects of a Single Sickling Event on the Mechanical Fragility of Sickle Trait Erythrocytes

Hemolysis contributes to the pathology associated with sickle cell disease. However, the mechanism of hemolysis or relative contribution of sickling due to hemoglobin polymerization vs. oxidative damage remains unknown. Earlier studies aimed at deciphering the relative importance of these two mechan...

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Hlavní autoři: Presley, Tennille D., Perlegas, Andreas S., Bain, Lauren E., Ballas, Samir K., Nichols, James S., Sabio, Hernan, Gladwin, Mark T., Kato, Gregory J., Kim-Shapiro, Daniel B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226741/
https://ncbi.nlm.nih.gov/pubmed/20113285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03630260903546999
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