Effects of a Single Sickling Event on the Mechanical Fragility of Sickle Trait Erythrocytes

Hemolysis contributes to the pathology associated with sickle cell disease. However, the mechanism of hemolysis or relative contribution of sickling due to hemoglobin polymerization vs. oxidative damage remains unknown. Earlier studies aimed at deciphering the relative importance of these two mechan...

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Main Authors: Presley, Tennille D., Perlegas, Andreas S., Bain, Lauren E., Ballas, Samir K., Nichols, James S., Sabio, Hernan, Gladwin, Mark T., Kato, Gregory J., Kim-Shapiro, Daniel B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226741/
https://ncbi.nlm.nih.gov/pubmed/20113285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03630260903546999
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